Aminobenzoic acids and derivatives
Medchemexpress LLC Gabexate (mesylate) | 56974-61-9 | 98.6% | 1 ML
Gabexate mesylate (FOY) is a competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases. It exhibits anticoagulant effects on thrombin's clotting activity and anti-inflammatory effects by inhibiting NF-κB, proinflammatory cytokines, and nitric oxide. This product is indicated for research use in pancreatitis and disseminated intravascular coagulation studies.
- Competitive and non-antigenic synthetic inhibitor of trypsin-like serine proteinases.
- Inhibits human thrombin, urokinase, plasmin, and Factor Xa.
- Binds to human and bovine tryptase.
- Demonstrates anticoagulant activity.
- Provides anti-inflammatory effects.
- Decreases proliferation rate in HepG2 cells in vitro.
- Attenuates mechanical allodynia in vivo.
Apexbio Technology LLC KB-R7943 mesylate 182004-65-5 10mM (in 1mL DMSO)
KB-R7943 mesylate (CAS 182004-65-5) is a selective inhibitor of the Na /Ca2 exchanger (NCX) particularly effective against its reverse mode It inhibits NCX-mediated Ca2 influx with an IC50 of 0 7 M In transfected Chinese hamster ovary (CHO) cells expressing NCX KB-R7943 suppresses exchanger activity at high intracellular Na concentrations In cultured rat forebrain neurons it attenuates Ca2 transients induced by glutamate NMDA kainate or KCl with IC50 values ranging from 2 9 to 8 2 M In in vivo studies KB-R7943 reduces endothelin-1 levels and mitigates acute renal dysfunction following ischemic injury This compound is widely utilized in studies investigating Na /Ca2 exchange and related calcium signaling pathways
Medchemexpress LLC Eribulin mesylate | 441045-17-6 | 99.3% | 826.00 | 10 MG
Eribulin mesylate is a microtubule targeting agent designed for metastatic breast cancer research. It effectively inhibits the proliferation of cancer cells by binding to microtubule proteins and microtubules, demonstrating significant activity both in vitro and in vivo.
- Inhibits cell proliferation in various cancer cell lines.
- Induces early apoptosis and G2/M arrest in LM8 cells.
- Suppresses cell migration at low concentrations.
- Reduces primary tumor growth and lung metastasis in osteosarcoma models.
- Suppresses circulating tumor cells.
Medchemexpress LLC PBT434 mesylate | 2387898-69-1 | 25 MG
PBT434 mesylate is the methanesulfonate salt of PBT434, a brain-penetrant, orally active small molecule inhibitor of α-synuclein aggregation used in preclinical Parkinson's disease research.
- Acts as an iron chelator and modulates transcellular iron trafficking.
- Inhibits iron-mediated redox activity and α-synuclein aggregation.
- Orally active and crosses the blood-brain barrier.
- Supplied as a mesylate salt, solid, white to off-white.
- High purity suitable for research (99.9%).
Apexbio Technology LLC Safinamide Mesylate 202825-46-5 50mg
Safinamide Mesylate (CAS 202825-46-5) is the mesylate salt form of safinamide a selective and reversible inhibitor of monoamine oxidase B (MAO-B) Safinamide exhibits an IC50 of 98 nM for MAO-B inhibition leading to enhanced dopaminergic transmission by reducing dopamine degradation In addition to MAO-B inhibition safinamide modulates sodium and calcium channels (IC50 8 2 M and 31 5 M respectively) and suppresses glutamate release ( 56 4 M) contributing to its anticonvulsant properties Research applications include the study of Parkinson s disease mechanisms and the investigation of dopaminergic and glutamatergic modulation
Selleck Chemical LLC Lenvatinib Mesylate S5240-10mM/1mL
Lenvatinib Mesylate is a synthetic orally available tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptor (VEGFR1-3) fibroblast growth factor receptor (FGFR1-4) platelet-derived growth factor receptor (PDGFR ) stem cell factor receptor (Kit (c-Kit)) and rearranged during transfection (RET (c-RET)) Lenvatinib Mesylate has potential antineoplastic activity
Medchemexpress LLC Pridinol mesylate | 6856-31-1 | 100.0% | 100 MG
Pridinol mesylate is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR)-directed muscle relaxant. It reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity.
- Inhibits skeletal muscle contractures in diseases of both central and peripheral origin.
- Can be used in research in the field of musculoskeletal diseases.
TARGETMOL CHEMICALS INC Phentolamine mesylate 500MG
Also available in 1 mL, 100 mg, 200 mg and bulk. Please contact Fisher for quotes. Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist used to treat hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of [RAYNAUD DISEASE] and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease. Purity 99.9%
Chemscene ChemScene | Diludine | 100g | CS-W018746 | 0.98 | 1149-23-1| MFCD00005951 | 253.3
ChemScene | Diludine | 100g | CS-W018746 | 0.98 | 1149-23-1| MFCD00005951 | 253.3
Chemscene 4-Benzylbenzenamine | 25g | CS-W020050 | 98% | 1135-12-2 | MFCD00047861 | 183 25 | C13H13N
Chemscene | 4-Benzylbenzenamine | 25g | CS-W020050 | 98% | 1135-12-2 | MFCD00047861 | 183 25 | C13H13N
Chemscene 3-Amino-9-ethylcarbazole | 5g | CS-W015102 | 98% | 132-32-1 | MFCD00004964 | 210 28 | C14H14N2
Chemscene | 3-Amino-9-ethylcarbazole | 5g | CS-W015102 | 98% | 132-32-1 | MFCD00004964 | 210 28 | C14H14N2